Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
GCOM1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
18129-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GCOM1 Fusion Protein Ag12708 (118-466 aa encoded by BC101645)
偶联物
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MYGDYDEMR QKIRQLTQEL SVSHAQQEYL ENHIQTQSSA LDRFNAMNSA LASDSIGLQK TLVDVTLENS NIKDQIRNLQ QTYEASMDKL REKQRQLEVA QVENQLLKMK VESSQEANAE VMREMTKKLY SQYEEKLQEE QRKHSAEKEA LLEETNSFLK AIEEANKKMQ AAEISLEEKD QRIGELDRLI ERMEKERHQL QLQLLEHETE MSGELTDSDK ERYQQLEEAS ASLRERIRHL DDMVHCQQKK VKQMVEEIES LKKKLQQKQL LILQLLEKIS FLEGENNELQ SRLDYLTETQ AKTEVETREI GVGCDLLPSQ TGRTREIVMP SRNYTPYTRV LELTMKKTLT (118-466 aa encoded by BC101645)
靶标信息
MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: gcom; Gcom2; GRINL1A; GRINL1A combined protein; GRINL1A complex locus 1; GRINL1A complex locus protein 1; GRINL1A complex locus upstream; GRINL1A upstream protein; Gup; myocardial intercalated disc protein; Myocardial zonula adherens protein; myocardium-enriched ZO1-associated protein; myocardium-enriched zonula adherens protein; myocardium-enriched zonula occludens-1-associated protein; myozap; MYZAP-POLR2M
基因别名: AA407270; AV006038; GCOM1; Gm640; Grinl1a7; Gup; MYOZAP; MYZAP
UniProt ID: (Human) Q6EM48, (Mouse) Q3UIJ9, (Rat) Q5EB94
Entrez Gene ID: (Human) 100820829, (Mouse) 102371, (Rat) 363091
