Immunogen sequence: YNINNSVSFS SAVKCVCNLM IKEPKSSSRT LGRAPYSFTF NSQFEFGKKH KWIQIDVTSL LQPLVASNKR SIHMSINFTC MKDQLEHP
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 58%.
GDF9 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. GDF9 is expressed in oocytes and is thought to be required for ovarian folliculogenesis.
蛋白别名: GDF-9; Growth/differentiation factor 9
UniProt ID: (Human) O60383
Entrez Gene ID: (Human) 2661
分子生物学功能: growth factor