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Alomone Labs, LTD
GFRAL (extracellular) Polyclonal Antibody
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GFRAL (extracellular) Antibody (ANT-029-200UL) in IHC (F)
Expression of GFRAL in rat nucleus of the solitary tract. Immunohistochemical staining of perfusion-fixed frozen rat brain sections using Anti-GFRAL (extracellular) Antibody (#ANT-029) (1:200), followed by goat anti-rabbit-AlexaFluor-488. A. GFRAL immunoreactivity (green) appears in cells lining the wall of the 4th ventricle (down pointing arrow) and in neurons in the nucleus of the solitary tract (horizont... View More
产品信息
ANT-029-200UL
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide HEPPFWDTPLNHG, corresponding to amino acid residues 92-104 of rat SLC10A4. Extracellular, N-terminus.
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunogen sequence: HEPPFWDTPLNHG
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846097, PubMed:28846098, PubMed:28846099). Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GDNF family receptor alpha-like; GDNF receptor alpha-like
基因别名: AY457637; Gfral; Gral; RGD1565220
UniProt ID: (Mouse) Q6SJE0, (Rat) D3ZB94
Entrez Gene ID: (Mouse) 404194, (Rat) 501023
