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Proteintech
GSR Polyclonal Antibody
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产品信息
18257-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GSR Fusion Protein Ag13080 (274-522 aa encoded by BC069244)
偶联物
形式
Liquid
浓度
0.17 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is specific to GSR.
Immunogen sequence: ISTNCTEEL ENAGVEVLKF SQVKEVKKTL SGLEVSMVTA VPGRLPVMTM IPDVDCLLWA IGRVPNTKDL SLNKLGIQTD DKGHIIVDEF QNTNVKGIYA VGDVCGKALL TPVAIAAGRK LAHRLFEYKE DSKLDYNNIP TVVFSHPPIG TVGLTEDEAI HKYGIENVKT YSTSFTPMYH AVTKRKTKCV MKMVCANKEE KVVGIHMQGL GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR (274-522 aa encoded by BC069244)
靶标信息
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; glutathione reductase; glutathione reductase 1; Glutathione reductase, mitochondrial; glutathione S-reductase; GR; GRase
基因别名: AI325518; D8Ertd238e; GLUR; Gr-1; Gr1; GRD1; GSR; HEL-75; HEL-S-122m
UniProt ID: (Human) P00390, (Mouse) P47791
Entrez Gene ID: (Human) 2936, (Mouse) 14782, (Rat) 116686
glutathione-disulfide reductase activity
electron carrier activity
flavin adenine dinucleotide binding
NADP binding
oxidoreductase activity
oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
protein homodimerization activity
glutathione binding
oxidoreductase
reductase
metabolite interconversion enzyme
