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Proteintech
Galc Polyclonal Antibody
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产品信息
11991-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Galc Fusion Protein Ag3914 (340-513 aa encoded by BC086671)
偶联物
形式
Liquid
浓度
0.34 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
The GALC antibody targets the liposomal enzyme Galactosylceramidase (GALC), which belongs to the glycosyl hydrolase 59 family. Normal GALC mRNA encodes the 80 kDa precursor, which is processed into 50 and 30 kDa subunits.
Immunogen sequence: YYLKTVGHL EKGGSYVALT DGLGNLTIII ETMSHQHSMC IRPYLPYYNV SHQLATFTLK GSLREIQELQ VWYTKLGTPQ QRLHFKQLDT LWLLDGSGSF TLELEEDEIF TLTTLTTGRK GSYPPPPSSK PFPTNYKDDF NVEYPLFSEA PNFADQTGVF EYYMNNEDRE HRFTL (340-513 aa encoded by BC086671)
靶标信息
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 3.2.1.46; beta-galactosidase; Galactocerebrosidase; Galactocerebroside beta-galactosidase; Galactosylceramidase; Galactosylceramide beta-galactosidase; galactosylceraminidase; GALCERase; testis tissue sperm-binding protein Li 88E; testis tissue sperm-binding protein Li 89A
基因别名: 2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; GALC; twi; twitcher
UniProt ID: (Human) B7Z7Z2, (Mouse) P54818
Entrez Gene ID: (Human) 2581, (Rat) 314360, (Mouse) 14420
