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MA5-18005 targets H-2Ld in FACS applications and shows reactivity with Mouse samples.
The MA5-18005 immunogen is mouse H-2Ld (public determinant H-2.65).
MHC Class I (H-2Ld) is a protein complex located on the surface of cells in vertebrates. Its main function is to present peptides derived from intracellular proteins to T cells for immune recognition. The structure of MHC Class I (H-2Ld) consists of a heavy chain, beta-2 microglobulin, and a peptide-binding groove that interacts with antigenic peptides. The location of MHC Class I (H-2Ld) varies depending on the cell type, but it is typically found on the surface of nucleated cells.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: H-2L; H2L; H2LD; histocompatibility 2, D region locus L; histocompatibility 2, L region
基因别名: H-2L
Entrez Gene ID: (Mouse) 14980