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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Expected to cross react with rat due to sequence homology.
MA1-20354 detects a band ~65 kDa by Western blot. Possible positive controls for this product are HeLa cell whole cell lysate.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp686H12203; HD1; Histone deacetylase 1; Protein deacetylase HDAC1; Protein decrotonylase HDAC1; reduced potassium dependency, yeast homolog-like 1; RP4-811H24.2
基因别名: HDAC1; RPD3L1