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Proteintech
HEC1/HEC/NDC80 Recombinant Rabbit Monoclonal Antibody (5A2), CoraLite® Plus 488
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产品信息
CL488-83859
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5A2
抗原
Fusion Protein
偶联物
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1000 µg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Sequence of this protein is as follows: LFGKRTSGHG SRNSQLGIFS SSEKIKDPRP LNDKAFIQQC IRQLCEFLTE NGYAHNVSMK SLQAPSVKDF LKIFTFLYGF LCPSYELPDT KFEEEVPRIF KDLGYPFALS KSSMYTVGAP HTWPHIVAAL VWLIDCIKIH TAMKESSPLF DDGQPWGEET EDGIMHNKLF LDYTIKCYES FMSGADSFDE MNAELQSKLK DLFNVDAFKL ESLEAKNRAL NEQIARLEQE REKEPNRLES LRKLKASLQG DVQKYQAYMS NLESHSAILD QKLNGLNEEI ARVELECETI KQENTRLQNI IDNQKYSVAD IERINHERNE LQQTINKLTK DLEAEQQKLW NEELKYARGK EAIETQLAEY HKLARKLKLI PKGAENSKGY DFEIKFNPEA GANCLVKYRA QVYVPLKELL NETEEEINKA LNKKMGLEDT LEQLNAMITE SKRSVRTLKE EVQKLDDLYQ QKIKEAEEED EKCASELESL EKHKHLLEST VNQGLSEAMN ELDAVQREYQ LVVQTTTEER RKVGNNLQRL LEMVATHVGS VEKHLEEQIA KVDREYEECM SEDLSENIKE IRDKYEKKAT LIKSSEE
靶标信息
Hec1 is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HEC-1; HEC2; HEC4; Highly expressed in cancer protein; highly expressed in cancer, rich in leucine heptad repeats; HsHec1; kinetochore associated 2; Kinetochore protein Hec1; Kinetochore protein NDC80 homolog; Kinetochore-associated protein 2; NDC80 homolog, kinetochore complex component; NDC80 kinetochore complex component homolog; Retinoblastoma-associated protein HEC
基因别名: HEC; HEC1; HsHec1; hsNDC80; KNTC2; NDC80; TID3
UniProt ID: (Human) O14777
Entrez Gene ID: (Human) 10403
mitotic sister chromatid segregation
establishment of mitotic spindle orientation
mitotic spindle organization
chromosome segregation
sister chromatid cohesion
mitotic nuclear division
attachment of spindle microtubules to kinetochore
cell division
attachment of mitotic spindle microtubules to kinetochore
