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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
对照试剂 (Ctrl) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属 |
Human |
表达系统 |
E. coli |
氨基酸序列 |
MAPLATRQGK RPSKNLKARC SRKALHVNFK DMGWDDWIIA PLEYEAFHCE GLCEFPLRSH LEPTNHAVIQ TLMNSMDPES TPPTCCVPTR LSPISILFIDSA NNVVYKQY EDMVVESCGC R |
分子量 |
13.7 kDa |
分类 |
Recombinant |
类型 |
Protein |
纯度 |
&(8)805;95% |
内毒素浓度 |
≤1 EU/µg |
活性 |
ED50 ≤ 1.2 µg/mL; determined by the dose-dependent ability to induce alkaline phosphatase activity in ATDC5 cells. |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
浓度 |
0.1 mg/mL |
纯化类型 |
purified |
保存液 |
0.1% TFA |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
Recombinant human GDF-5 is a non-glycosylated homodimer containing two 120 amino acids chains. To enable bacterial expression the N-terminal sequence of Ala-Pro-Leu-Thr was replaced with a Lys.
Reconstitute using sterile water at 0.1 mg/mL and centrifuge prior to opening vial. Gently pipet solution down the sides of the vial. DO NOT VORTEX sample. Store reconstituted material at -20°C and add 0.1% BSA for additional stability.
Growth/Differentiation Factor 5 (GDF-5) is a growth factor that regulates cell proliferation and differentiation in embryonic and adult tissues. GDF-5 is part of the TGF family of proteins and is closely related to the BMP family of proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: BMP-14; Bone morphogenetic protein 14; Cartilage-derived morphogenetic protein 1; cartilage-derived morphogenetic protein-1; CDMP-1; GDF-5; Growth/differentiation factor 5; H-GDF-5; LAP-4; Lipopolysaccharide-associated protein 4; LPS-associated protein 4; Radotermin
基因别名: BDA1C; BMP-14; BMP14; CDMP1; GDF5; LAP-4; LAP4; OS5; SYM1B; SYNS2
UniProt ID: (Human) P43026
Entrez Gene ID: (Human) 8200
分子生物学功能:
growth factor
