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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
免疫组化 (IHC) |
Assay-dependent | - |
酶联免疫吸附实验 (ELISA) |
Assay-dependent | - |
功能检测 (FN) |
Assay-dependent | - |
对照试剂 (Ctrl) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属 |
Human |
表达系统 |
E. coli |
氨基酸序列 |
Human IL-18, amino acids 37-193 |
分子量 |
18 kDa |
分类 |
Recombinant |
类型 |
Protein |
纯度 |
>90% by SDS-PAGE |
内毒素浓度 |
<0.1 ng/µg |
活性 |
Determined by the dose-dependent production of IFN-gamma by human KG-1 myelomonocyte cells. |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
纯化类型 |
sequential chromatography |
保存液 |
PBS with 0.1% BSA, 1% sucrose |
内含物 |
no preservative |
保存条件 |
-20°C |
Reconstitution: We recommend the vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute with 250 µL ice cold, sterile, distilled water on ice.
Storage: Store this lyophilized preparation at -20°C, preferably desiccated. Upon reconstitution, the protein may be stored at 2°C to 8°C for up to one week. For long term storage of the reconstituted protein, apportion into working aliquots and store at -80°C. Avoid repeated freeze/thaw cycles.
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Iboctadekin; IFN-gamma-inducing factor; il 18; IL-1 gamma; IL-18; ILN; Interferon gamma-inducing factor; Interleukin; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; Interleukin-18; Interleukin18; MGC12320
基因别名: IGIF; IL-18; IL-1g; IL18; IL1F4
UniProt ID: (Human) Q14116
Entrez Gene ID: (Human) 3606
分子生物学功能:
cytokine
interleukin superfamily
intercellular signal molecule
