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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
Assay-dependent | - |
对照试剂 (Ctrl) |
Assay-dependent | - |
| 产品规格 | |
|---|---|
种属 |
Human |
表达系统 |
E. coli |
氨基酸序列 |
Human PON1 recombinant protein contains an N-terminal His-tag |
标签 |
His-tag |
分子量 |
42.9 kDa |
分类 |
Recombinant |
类型 |
Protein |
纯度 |
95% by SDS-PAGE |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
0.69 mg/mL |
纯化类型 |
purified |
保存液 |
20mM tris HCl with 50% glycerol |
内含物 |
no preservative |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
This product contains purified recombinant human Paraoxonase 1 protein with an N-terminal hexahistidine tag.
This product may be used as a positive control in many immunological assays.
The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: A esterase 1; A-esterase 1; Aromatic esterase 1; arylesterase 1; arylesterase B-type; EC 3.1.1.2; EC 3.1.1.81; EC 3.1.8.1; ESAesterase A; esterase A; K-45; paraoxonase B-type; PON 1; serum aryldiakylphosphatase; Serum aryldialkylphosphatase 1; Serum paraoxonase/arylesterase 1
基因别名: ESA; MVCD5; PON; PON1
UniProt ID: (Human) P27169
Entrez Gene ID: (Human) 5444
