Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ICSA Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
ICSA Antibody (PA5-144412) in WB
Western blot analysis of ICSA in recombinant protein using a dilution of 1:2,000. Samples were incubated with ICSA polyclonal antibody (Product # PA5-144412). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 40.3 kDa. Observed band size: 45 kDa.
产品信息
PA5-144412
产品规格
种属反应
Bacteria
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Shigella flexneri ICSA protein (311-547aa)
偶联物
形式
Liquid
浓度
1.745 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
An immunogenic protein essential for bacterial spreading, it elicits polar deposition of filamentous actin (actin-based motility) (PubMed:2542950, PubMed:8702989). Inside the host (human) cell mediates nucleation and polymerization of actin molecules on the bacterial surface, which provides the propulsive force for intracellular movement and intercellular dissemination of the bacterium (PubMed:2644195, PubMed:8468279, PubMed:2542950). During invasion of mammalian cells, triggers autophagy by binding to host ATG5. Interaction with IcsB leads to escape from the host autophagy defense system (PubMed:15576571). Binds ATP and displays weak ATPase activity (PubMed:8468279). Mediates polar adhesion to host cells and their invasion. The bile salt deoxycholate activates adhesion and invasion of host cells, possibly by altering IcsA's conformation. The adhesion and intercellular dissemination phenotypes can be separated (PubMed:24721572).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: virG
