The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
蛋白别名: alpha-pregnancy-associated endometrial globulin; amniotic fluid binding protein; Binding protein 25; Binding protein 26; Binding protein 28; binding protein-25; binding protein-26; binding protein-28; growth hormone independent-binding protein; hIGFBP 1; hIGFBP1; IBP 1; IBP-1; IGF BP25; IGF-binding protein 1; IGFBP; IGFBP 1; IGFBP-1; Insulin like growth factor binding protein; insulin-like growth factor binding protein 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); Insulin-like growth factor-binding protein 1; Placental protein 12; PP 12; PP12
基因别名: AFBP; hIGFBP-1; IBP1; IGF-BP25; IGFBA; Igfbp-1; IGFBP1; PP12
分子生物学功能: protease inhibitor