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Invitrogen
IL11RA Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-144769
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RYLTSYRKKT VLGADSQRRS PSTGPWPCPQ DPLGAARCVV HGAEFWSQYR INVTEVNPLG ASTRLLDVSL QSILRPDPPQ GLRVESVPGY P
Antigen sequence identity: Mouse 90%; Rat 89%
靶标信息
Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IL-11 receptor subunit alpha; IL-11R subunit alpha; interleukin 11 receptor, alpha; interleukin-11 receptor alpha chain; sIL11RA; unnamed protein product
基因别名: CRSDA
UniProt ID: (Human) Q14626
Entrez Gene ID: (Human) 3590
negative regulation of cytokine-mediated signaling pathway
embryo implantation
positive regulation of cell proliferation
cytokine-mediated signaling pathway
B cell differentiation
megakaryocyte differentiation
developmental process
interleukin-11-mediated signaling pathway
positive regulation of MAPK cascade
negative regulation of cytokine activity
head development
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