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Proteintech
IL17RE Polyclonal Antibody
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产品信息
11984-1-AP
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IL17RE Fusion Protein Ag2612 (1-271 aa encoded by BC063110)
偶联物
形式
Liquid
浓度
0.23 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MGSSRLAAL LLPLLLIVID LSDSAGIGFR HLPHWNTRCP LASHTDDSFT GSSAYIPCRT WWALFSTKPW CVRVWHCSRC LCQHLLSGGS GLQRGLFHLL VQKSKKSSTF KFYRRHKMPA PAQRKLLPRR HLSEKSHHIS IPSPDISHKG LRSKRTQPSD PETWESLPRL DSQRHGGPEF SFDLLPEARA IRVTISSGPE VSVRLCHQWA LECEELSSPY DVQKIVSGGH TVELPYEFLL PCLCIEASYL QEDTVRRKKC PFQSWPEACE CC (1-271 aa encoded by BC063110)
靶标信息
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: IL-17 receptor E; Interleukin-17 receptor E
基因别名: AA589509; IL-17RE; IL17RE; Il25r; UNQ3056/PRO9877
UniProt ID: (Human) Q8NFR9, (Mouse) Q8BH06
Entrez Gene ID: (Human) 132014, (Mouse) 57890
