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Invitrogen
INTS6 Polyclonal Antibody
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产品信息
PA5-51643
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VVNNHIGGKG PPAPTTQAQP DLIKPLPLHK ISETTNDSII HDVVENHVAD QLSSDITPNA MDTEFSASSP ASLLERPTNH MEALGHDHLG TNDLTVGGFL ENHEEPRDKE QCAEENIPAS SLNKGKKLMH CRSHEEVNTE LKAQ
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.
靶标信息
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. INTS6 is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DBI-1; DEAD box protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26; DICE1; DKFZP434B105; Int6; Integrator complex subunit 6; Protein DDX26; Protein deleted in cancer 1; RNA helicase HDB
基因别名: DBI-1; DBI1; DDX26; DDX26A; DICE1; HDB; INT6; INTS6; Notchl2
UniProt ID: (Human) Q9UL03
Entrez Gene ID: (Human) 26512
