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Invitrogen
IRX3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-144938
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.05 mg/mL
规格
5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: GEEEDTGGEG LADDDEDEEI DLENLDGAAT EPELSLAGAA RRDGDLGLGP I
Antigen sequence identity: Mouse 84%; Rat 82%
靶标信息
IRX3 is a member of the Iroquois homeobox gene family (seeIRX1; MIM 606197) and plays a role in an early step of neural development. Members of this family appear to play multiple roles during pattern formation of vertebrate embryos.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: homeodomain protein IRXB1; iroquois homeobox protein 3; iroquois-class homeodomain protein IRX-1
基因别名: IRX-1; IRXB1
UniProt ID: (Human) P78415
Entrez Gene ID: (Human) 79191
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
metanephros development
Purkinje myocyte development
atrioventricular bundle cell differentiation
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
cell development
His-Purkinje system cell differentiation
proximal/distal pattern formation involved in nephron development
specification of loop of Henle identity
energy homeostasis
regulation of cell communication by electrical coupling involved in cardiac conduction
positive regulation of gap junction assembly
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