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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:500-1:2,000 | - |
免疫组化（石蜡） (IHC (P)) |
1:50 - 1:200 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
Recombinant fusion protein containing a sequence corresponding to amino acids 585-815 of human KDM4A. |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
3.35 mg/mL |
纯化类型 |
Antigen affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808681 |
Immunogen sequence: FSLEENKKSK GRRQPLSKLP RHHPLVLQEC VSDDETSEQL TPEEEAEETE AWAKPLSQLW QNRPPNFEAE KEFNETMAQQ APHCAVCMIF QTYHQVEFGG FNQNCGNASD LAPQKQRTKP LIPEMCFTST GCSTDINLST PYLEEDGTSI LVSCKKCSVR VHASCYGVPP AKASEDWMCS RCSANALEED CCLCSLRGGA LQRANDDRWV HVSCAVAILE ARFVNIAERS P; Positive Samples: BT-474, THP-1, Mouse thymus; Cellular Location: Nucleus
JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: [histone H3]-trimethyl-L-lysine(36) demethylase 4A; [histone H3]-trimethyl-L-lysine(9) demethylase 4A; JmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji domain containing 2A; Jumonji domain-containing protein 2A; lysine (K)-specific demethylase 4A; Lysine-specific demethylase 4A; tudor domain containing 14A
基因别名: D4Ertd222e; JHDM3A; JMJD2; JMJD2A; KDM4A; KIAA0677; mKIAA0677; TDRD14A
UniProt ID: (Human) O75164, (Mouse) Q8BW72
Entrez Gene ID: (Human) 9682, (Mouse) 230674
分子生物学功能:
histone modifying enzyme
