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Invitrogen
KCC3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-56975
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RVRFSSRESV PETSRSEPMS EMSGATTSLA TVALDPPSDR TSHPQDVIED LSQNSITGEH SQLLDDGHKK ARNAYLNNSN YEEGDE
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 93%.
靶标信息
SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DKFZP434D2135; electroneutral potassium-chloride cotransporter 3; K-Cl cotransporter 3; KCC3; KCC3a exon 1a splice variant; KCC3a exon 1a splice variant 2; KCC3a exon 2 splice variant; potassium chloride cotransporter 3; potassium chloride cotransporter KCC3a-S3; potassium-chloride transporter-3a; potassium-chloride transporter-3b; SLC121A6; solute carrier family 12 (potassium/chloride transporter), member 6; solute carrier family 12 (potassium/chloride transporters), member 6; unnamed protein product
基因别名: ACCPN; CMT2II; KCC3; KCC3A; KCC3B
UniProt ID: (Human) Q9UHW9
Entrez Gene ID: (Human) 9990
angiogenesis
ion transport
chloride transport
cell volume homeostasis
chloride ion homeostasis
potassium ion homeostasis
transmembrane transport
cellular hypotonic response
cellular hypotonic salinity response
potassium ion transmembrane transport
chloride transmembrane transport
potassium ion import across plasma membrane
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
