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Immunogen sequence: PHFIAKRVTYD SDATSSACRE
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
Negatively regulates leptin receptor (LEPR) cell surface expression, and thus decreases response to leptin. Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DnaJ (Hsp40) homolog, subfamily C, member 6; Endospanin-1; leptin receptor gene related protein; Leptin receptor gene-related protein; Leptin receptor overlapping transcript protein; OB-R gene-related protein; OB-RGRP
基因别名: LEPR; LEPROT; OB-RGRP; OBR; OBRGRP; VPS55
UniProt ID: (Human) O15243
Entrez Gene ID: (Human) 54741
分子生物学功能: transmembrane signal receptor