Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
LRRC4C Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
13845-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
LRRC4C Fusion Protein Ag4811 (45-351 aa encoded by BC041374)
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: QTCPSVCSC SNQFSKVICV RKNLREVPDG ISTNTRLLNL HENQIQIIKV NSFKHLRHLE ILQLSRNHIR TIEIGAFNGL ANLNTLELFD NRLTTIPNGA FVYLSKLKEL WLRNNPIESI PSYAFNRIPS LRRLDLGELK RLSYISEGAF EGLSNLRYLN LAMCNLREIP NLTPLIKLDE LDLSGNHLSA IRPGSFQGLM HLQKLWMIQS QIQVIERNAF DNLQSLVEIN LAHNNLTLLP HDLFTPLHHL ERIHLHHNPW NCNCDILWLS WWIKDMAPSN TACCARCNTP PNLKGRYIGE LDQNYFTC (45-351 aa encoded by BC041374 )
靶标信息
Leucine-rich repeat-containing 4C (LRRC4C), also known as Netrin-G ligand 2 (NGL-2), is a gene highlighted for its expression in the nervous system, particularly the brain. It is a member of the leucine-rich repeat superfamily, which plays a significant role in cell adhesion and signaling pathways critical for synaptic connectivity and neuronal development. LRRC4C is involved in neural processes such as axon guidance and synapse formation, aiding in the establishment of functional neural circuits. Additionally, research has suggested that LRRC4C may function as a tumor suppressor, particularly in gliomas, indicating its potential role in neuro-oncological disorders. Variations or deletions in this gene have been linked to neurodevelopmental disorders, demonstrating its importance in normal brain function and development. Furthermore, LRRC4C's expression patterns and associations with cancer also suggest its potential as a prognostic marker in clinical settings.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Leucine-rich repeat-containing protein 4C; Netrin-G1 ligand; NGL-1
基因别名: 6430556C10Rik; KIAA1580; LRRC4C; NGL-1; NGL1; RGD1311013; UNQ292/PRO331
UniProt ID: (Human) Q9HCJ2, (Mouse) Q8C031
Entrez Gene ID: (Human) 57689, (Mouse) 241568, (Rat) 311236
