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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: STTNAIAPVS CSSNEGASSQ DEKSLGSSRE AEGWKEDPLN KKVVSLVHFL LQKYETKEPI T
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 41%.
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAGBI; MAGE-B18 antigen; Melanoma-associated antigen B18
基因别名: MAGEB18
Entrez Gene ID: (Human) 286514