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Invitrogen
MT1 Polyclonal Antibody
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MT1 Antibody (PA5-144456) in WB
Western blot analysis of MT1 in recombinant protein using a dilution of 1:2,000. Samples were incubated with MT1 polyclonal antibody (Product # PA5-144456). Secondary: Goat polyclonal to rabbit IgG at 1:50,000 dilution. Predicted band size: 12 kDa. Observed band size: 18 kDa.
产品信息
PA5-144456
产品规格
种属反应
C. elegans
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Caenorhabditis elegans MT1 protein
偶联物
形式
Liquid
浓度
4.5 mg/mL
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% Proclin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Metallothionein; Metallothionein-1; Metallothionein-I; MT-1; MT-I
基因别名: CELE_K11G9.6; K11G9.6; met-1; mtl-1
UniProt ID: (C. elegans) P17511
Entrez Gene ID: (C. elegans) 179060
