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Invitrogen
MTCH2 Polyclonal Antibody
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MTCH2 Antibody (PA5-78452) in IHC (P)
MTCH2 Polyclonal Antibody detects MTCH2 protein at cytoplasm in mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. MTCH2 Polyclonal Antibody (Product # PA5-78452) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
PA5-78452
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human MTCH2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
2.49 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: MCF-7, MCF-7 MF
Predicted Reactivity: Rat (88%), Rhesus Monkey (100%), Bovine (89%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2310034D24Rik; Met-induced mitochondrial protein; Mitochondrial carrier homolog 2; solute carrier family 25, member 50
基因别名: 2310034D24Rik; 4930539J07Rik; HSPC032; MIMP; MTCH2; SLC25A50
UniProt ID: (Human) Q9Y6C9, (Mouse) Q791V5
Entrez Gene ID: (Human) 23788, (Mouse) 56428
