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Proteintech
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Immunogen sequence: RYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR EQKFRLKRCG LERRVYLVEE HGSVHNLSLP ESTLLQAVTN TQVIDGFFVK RTADIKESAA YLALLTRGLQ RLYQGHTLRS RPWGTPGNPE SGAMTSPNPL CSLLTFSDFN AGAIKNKAQS VREVFARQLM QVRGVSGEKA AALVDRYSTP ASLLAAYDAC ATPKEQETLL STIKCGRLQR NLGPALSRTL SQLYCSYGPL T (202-551 aa encoded by BC009999)
Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog
基因别名: 1200008A18Rik; AI182501; AW045863; MUS81; SLX3
UniProt ID: (Human) Q96NY9, (Rat) Q4KM32, (Mouse) Q91ZJ0
Entrez Gene ID: (Human) 80198, (Rat) 293678, (Mouse) 71711