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Invitrogen
MYO1C Polyclonal Antibody
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MYO1C Antibody (PA5-93297) in IHC (P)
Immunohistochemistry analysis of MYO1C in paraffin-embedded mouse kidney. Samples were incubated with MYO1C Polyclonal antibody (Product # PA5-93297) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-93297
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein (or fragment)
偶联物
形式
Liquid
浓度
1.88 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ENAFFLDHVR TSFLLNLRRQ LPQNVLDTSW PTPPPALREA SELLRELCIK NMVWKYCRSI SPEWKQQLQQ KAVASEIFKG KKDNYPQSVP RLFISTRLGT DEISPRVLQA LGSEPIQYAV PVVKYDRKGY KPRSRQLLLT PNAVVIVEDA KVKQRIDYAN LTGISVSSLS DSLFVLHVQR ADNKQKGDVV LQSDHVIETL TKTALSANRV NSININQGSI TFAGGPGRDG TIDFTPGSEL LITKAKNGHL AVVAPRLNSR; Positive Samples: HT-29, SKOV3, Mouse lung, Rat lung; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Nucleus, Peripheral membrane protein, nuclear pore complex, nucleolus, nucleoplasm, ruffle, stereocilium membrane
靶标信息
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ23903; MMI-beta; MMIb; Myosin heavy chain myr 2; Myosin I beta; myosin IC-like; myosin-I beta; myosin-Ibeta; myosin-Ic; nuclear myosin I; nuclear myosin I beta; unconventional myosin Myr2 I heavy chain; Unconventional myosin-Ic
基因别名: C80397; mm1beta; MMI-beta; MMIb; MYO1C; MYO1E; Myr2; NMI
UniProt ID: (Human) O00159, (Rat) Q63355, (Mouse) Q9WTI7
Entrez Gene ID: (Human) 4641, (Rat) 65261, (Mouse) 17913
protein targeting
protein targeting to membrane
positive regulation of cell migration
positive regulation of cell migration by vascular endothelial growth factor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of gene expression, epigenetic
mRNA transport
positive regulation of protein targeting to membrane
positive regulation of vascular endothelial growth factor signaling pathway
regulation of bicellular tight junction assembly
transport
metabolic process
protein transport
