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Proteintech
MYOT Polyclonal Antibody
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产品信息
10731-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MYOT Fusion Protein Ag1112 (191-498 aa encoded by BC005376)
偶联物
形式
Liquid
浓度
0.18 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody can detect both of isoforms around 57 kDa and 35 kDa.
Immunogen sequence: GPQNAAAVF QAQDDSGAQD SQQHNSEHAR LQVPTSQVRS RSTSRGDVND QDAIQEKFYP PRFIQVPENM SIDEGRFCRM DFKVSGLPAP DVSWYLNGRT VQSDDLHKMI VSEKGLHSLI FEVVRASDAG AYACVAKNRA GEATFTVQLD VLAKEHKRAP MFIYKPQSKK VLEGDSVKLE CQISAIPPPK LFWKRNNEMV QFNTDRISLY QDNTGRVTLL IKDVNKKDAG WYTVSAVNEA GVTTCNTRLD VTARPNQTLP APKQLRVRPT FSKYLALNGK GLNVKQAFNP EGEFQRLAAQ SGLYESEEL (191-498 aa encoded by BC005376)
靶标信息
This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 57 kDa cytoskeletal protein; Myofibrillar titin-like Ig domains protein; Myotilin; titan-like protein; Titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin)
基因别名: 5530402I04Rik; LGMD1; LGMD1A; MFM3; Myo; MYOT; TTID; TTOD
UniProt ID: (Human) Q9UBF9, (Mouse) Q9JIF9
Entrez Gene ID: (Human) 9499, (Mouse) 58916, (Rat) 291605
