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Invitrogen
Mitofilin Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
Mitofilin Antibody (PA5-96203) in WB
Western blot was performed using Anti-Mitofilin Polyclonal Antibody (Product # PA5-96203) and a 83 kDa band corresponding to Mitofilin was observed across all tested cell line lysates. Whole cell extracts (30 µg lysate) of MCF7 (Lane 1), A549 (Lane 2), HEK-293 (Lane 3), U-2 OS (Lane 4) and HeLa (Lane 5) were electrophoresed using NuPAGE™ 10% Bis-Tris Protein Gel (Product # NP0302BOX), 12 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry Blotting System (Product # IB21001). The ... View More
Product Details
PA5-96203
产品规格
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 120-270 of human IMMT.
Conjugate
Unconjugated
形式
Liquid
浓度
0.29 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
RRID
AB_2808005
Product Specific Information
Immunogen sequence: ESKQPASQLQ KQKGDTPASA TAPTEAAQII SAAGDTLSVP APAVQPEESL KTDHPEIGEG KPTPALSEEA SSSSIRERPP EEVAARLAQQ EKQEQVKIES LAKSLEDALR QTASVTLQAI AAQNAAVQAV NAHSNILKAA MDNSEIAGEK K; Positive Samples: MCF7, B cells, HeLa, HepG2, SH-SY5Y, HL-60, Mouse kidney; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Single-pass membrane protein
Target Information
Mitofilin is a transmembrane protein of the inner mitochondrial membrane and it is associated with a large multimeric protein complex of about 1200 kDa. Mitofilin has critical functions in mitochondrial morphology and mitochondrial fusion and fission, specifically in the formation of tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been implicated in many human diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma and Whartin's tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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Bioinformatics
Protein Aliases: Cell proliferation-inducing gene 4/52 protein; cell proliferation-inducing protein 52; IMMT antibody; MICOS complex subunit MIC60; mitochondrial inner membrane organizing system 2; Mitochondrial inner membrane protein; Mitofilin; motor protein; p87/89; p87/89 antibody; proliferation-inducing gene 4
Gene Aliases: 1700082C19Rik; D830041H16Rik; HMP; IMMT; MIC60; MINOS2; P87; P87/89; P89; PIG4; PIG52
UniProt ID: (Human) Q16891, (Mouse) Q8CAQ8
Entrez Gene ID: (Human) 10989, (Mouse) 76614
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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