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Proteintech
NCL Polyclonal Antibody
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产品信息
10556-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Insect,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NCL Fusion Protein Ag0859 (1-482 aa encoded by BC006494)
偶联物
形式
Liquid
浓度
0.24 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MVKLAKAGK NQGDPKKMAP PPKEVEEDSE DEEMSEDEED DSSGEEVVIP QKKGKKAAAT SAKKVVVSPT KKVAVATPAK KAAVTPGKKA AATPAKKTVT PAKAVTTPGK KGATPGKALV ATPGKKGAAI PAKGAKNGKN AKKEDSDEEE DDDSEEDEED DEDEDEDEDE IEPAAMKAAA AAPASEDEDD EDDEDDEDGK SKGIAYIEFK TEADAEKTFE EKQGTEIDGR SISLYYTGEK GQNQDYRGGK NSTWSGESKT LVLSNLSYSA TEETLQEVFE KATFIKVPQN QNGKSKGYAF IEFASFEDAK EALNSCNKRE IEGRAIRLEL QGPRGSPNAR SQPSKTLFVK GLSEDTTEET LKESFDGSVR ARIVTDRETG SSKGFGFVDF NSEEDAKAAK EAMEDGEIDG NKVTLDWAKP KGEGGFGGRG GGRGGFGGRG GGRGGRGGFG GRGRGGFGGR GGFRGGRGGG GDHKPQGKKT KFE (1-482 aa encoded by BC006494)
靶标信息
Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ45706; FLJ59041; nucl antibody; Nucleolin; nucleolin-like protein; Protein C23
基因别名: B530004O11Rik; C23; D0Nds28; D1Nds28; NCL; Nuc; Nucl
UniProt ID: (Human) P19338, (Mouse) P09405
Entrez Gene ID: (Human) 4691, (Mouse) 17975, (Rat) 25135
nucleotide binding
single-stranded DNA binding
RNA binding
calcium ion binding
protein binding
protein C-terminus binding
selenocysteine insertion sequence binding
rRNA primary transcript binding
telomeric DNA binding
histone binding
identical protein binding
laminin binding
poly(A) RNA binding
ErbB-4 class receptor binding
nucleic acid binding
DNA binding
receptor binding
sequence-specific DNA binding
angiogenesis
endocytosis
spermatogenesis
positive regulation of tumor necrosis factor production
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
liver regeneration
positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
regulation of rRNA processing
positive regulation of interleukin-6 secretion
