Proteintech

NFX1 Recombinant Rabbit Monoclonal Antibody (230211D9)

Name: NFX1 Recombinant Rabbit Monoclonal Antibody (230211D9)
Brand: Proteintech
SKU: 82924-1-RR

查看其他8个NFX1抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

NFX1 Antibody in Immunocytochemistry (ICC/IF)

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NFX1 Antibody (82924-1-RR) in ICC/IF

Immunofluorescent analysis of (4% PFA) fixed HeLa cells using NFX1 antibody (82924-1-RR, Clone: 230211D9) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG (H+L) (SA00013-2).

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Immunogen image

Immunogen Image NFX1 Recombinant Rabbit Monoclonal Antibody (230211D9)

产品信息

82924-1-RR

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1:200-1:800

流式细胞分析 (Flow)

0.25 µg/10^6 cells in a 100 µL suspension

酶联免疫吸附实验 (ELISA)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

Expression System

CHO cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

230211D9

抗原

NFX1 fusion protein Ag9448

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

产品详细信息

Immunogen sequence: TCARVHECDH PVYHSCHSEE KCPPCTFLTQ KWCMGKHEFR SNIPCHLVDI SCGLPCSATL PCGMHKCQRL CHKGECLVDE PCKQPCTTPR ADCGHPCMAP CHTSSPCPVT ACKAKVELQC ECGRRKEMVI CSEASSTYQR IAAISMASKI TDMQLGGSVE ISKLITKKEV HQARLECDEE CSALERKKRL AEAFHISEDS DPFNIRSSGS KFSDSLKEDA RKDLKFVSDV EKEMETLVEA VNKGKNSKKS HSFPPMNRDH RRIIHDLAQV YGLESVSYDS EPKRNVVVTA IRGKSVCPPT TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD

靶标信息

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma.MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

仅用于科研。不用于诊断过程。未经明确授权不得转售。