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Invitrogen
NPFF2 Polyclonal Antibody
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NPFF2 Antibody (PA5-88020) in WB
Western blot analysis of NPFF2 in extracts of various cell lines. Samples were incubated with NPFF2 Polyclonal antibody (Product # PA5-88020) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-88020
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human NPFFR2 (NP_0048762)
偶联物
形式
Liquid
浓度
1.69 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MNSFFGTPAA SWCLLESDVS SAPDKEAGRE RRALSVQQRG GPAWSGSLEW SRQSAGDRRR LGLSRQTAKS SWSRSRDRTC CCRRAWWILV PAADRARRER FIMNEKWDTN SSENWHPIWN VNDTKHHLYS DINITYVNYY; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor 74; G-protein coupled receptor 74; Neuropeptide FF receptor 2; Neuropeptide G-protein coupled receptor; Neuropeptide NPFF receptor; NPFF-R2; NPFF2 receptor; NPGP receptor
基因别名: Gpr74; HG31; NPFF2; Npffr2; Npgpr
UniProt ID: (Rat) Q9EQD2, (Mouse) Q924H0
Entrez Gene ID: (Rat) 78964, (Mouse) 104443
neuropeptide signaling pathway
chemical synaptic transmission
cellular response to hormone stimulus
regulation of MAPK cascade
regulation of adenylate cyclase activity
response to peptide
regulation of cAMP-dependent protein kinase activity
signal transduction
G-protein coupled receptor signaling pathway
