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GenScript
Nivolumab Monoclonal Antibody (6G5), Biotin
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Nivolumab Antibody (A01848-40) in ELISA
Anti-Niolumab Antibody (6G5) [Biotin], mAb, Mouse (GenScript, A01848-40) binds with Niolumab, while the antibody does not recognize human IgG Fc fragment (data not shown). Coating antigen: Niolumab, 1 µg/mL. Anti-Niolumab antibody (GenScript, A01848-40) dilution start from 1,000 ng/mL. EC50= 3.01ng/mL.
产品信息
A01848-40
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
6G5
抗原
Nivolumab
偶联物
形式
Lyophilized
纯化类型
Protein A
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. GenScript Anti-Nivolumab Antibody (6G5) [Biotin], mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with Nivolumab.
Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below.
靶标信息
Nivolumab (Opdivo) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Nivolumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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