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Proteintech
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Immunogen sequence: PKQIVKSLIP SWNKLVFFEV SPVSFHQVSE VLSEEKSRLS ISGWFHGPSL TRPPNYFEPP IPRSPHIPQD HEILYDWINP TYLDMDYQVQ IQEEFEESSE ILLKEFLKPE KFTKVCEALE HGHVEWSSRG PPNKRFYEKA EESKLPEILK ECMKLFRSEA LFLLLSNFTG LKLHFLAPSE EDEMNDKKEA ETTDITEEGT SHSPPEPENN QMAISNNSQQ SNEQTDPEPE ENETKKESSV PMCQGELRHW KTGHYTLIHD HSKAEFALDL ILYCGCEGWE PEYGGFTSYI AKGEDEELLT VNPESNSLAL VYRDRETLKF VKHINHRSLE QKKTFPNRTG FWDFSFIYYE
OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 2-oxoglutarate and iron-dependent oxygenase domain containing 1; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1; Prolyl 3-hydroxylase OGFOD1; Termination and polyadenylation 1 homolog; TPA1, termination and polyadenylation 1, homolog; uS12 prolyl 3-hydroxylase
基因别名: KIAA1612; OGFOD1; TPA1
UniProt ID: (Human) Q8N543
Entrez Gene ID: (Human) 55239