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Proteintech
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Immunogen sequence: ERMQSVAAF AVSAVASQWE RTGKPFNPLL GETYELIRED LGFRFISEQV SHHPPISAFH SEGLNHDFLF HGSIYPKLKF WGKSVEAEPR GTITLELLKH NEAYTWTNPT CCVHNVIIGK LWIEQYGTVE ILNHRTGHKC VLHFKPCGLF GKELHKVEGH IQDKNKKKLF MIYGKWTECL WGIDPVSYES FKKQERRGDH LRKAKLDEDS GKADSDVADD VPVAQETVQV IPGSKLLWRI NTRPPNSAQM YNFTSFTVSL NELETGMEKT LPPTDCRLRP DIRGMENGNM DLASQEKERL EEKQREARRE RAKEEAEWQT RWFYPGNNPY TGTPDWLYAG DYFERNFSDC PDIY (128-480 aa encoded by B C000296)
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ20223; MGC4307; MGC8342; ORP-2; OSBP-related protein 2; oxysterol binding protein-like 2; oxysterol-binding protein-like 2; Oxysterol-binding protein-related protein 2; RP11-157P1.2
基因别名: C130070J12Rik; DFNA67; DNFA67; KIAA0772; mKIAA0772; ORP-2; ORP2; OSBPL2
UniProt ID: (Human) Q9H1P3, (Mouse) Q8BX94
Entrez Gene ID: (Human) 9885, (Mouse) 228983