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Alomone Labs, LTD
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Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dynamin PRD-interacting protein; Dynamin proline-rich domain-interacting protein; Protein kinase C and casein kinase substrate in neurons protein 1; SdpI; Synaptic, dynamin-associated protein I; syndapin 1; Syndapin I; Syndapin-1; Syndapin-I
基因别名: A830061D09Rik; H74; KIAA1379; mKIAA1379; Pacsin; PACSIN1; SDPI; syndapin
UniProt ID: (Human) Q9BY11, (Mouse) Q61644, (Rat) Q9Z0W5
Entrez Gene ID: (Human) 29993, (Mouse) 23969, (Rat) 29704