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Proteintech
PACSIN2 Polyclonal Antibody
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产品信息
10518-2-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human,
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
PACSIN2 Fusion Protein Ag0809 (180-486 aa encoded by BC008037)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: PSLNPEQLK KLQDKIEKCK QDVLKTKEKY EKSLKELDQG TPQYMENMEQ VFEQCQQFEE KRLRFFREVL LEVQKHLDLS NVAGYKAIYH DLEQSIRAAD AVEDLRWFRA NHGPGMAMNW PQFEEWSADL NRTLSRREKK KATDGVTLTG INQTGDQSLP SKPSSTLNVP SNPAQSAQSQ SSYNPFEDED DTGSTVSEKD DTKAKNVSSY EKTQSYPTDW SDDESNNPFS STDANGDSNP FDDDATSGTE VRVRALYDYE GQEHDELSFK AGDELTKMED EDEQGWCKGR LDNGQVGLYP ANYVEAIQ (180-486 aa encoded by BC008037)
靶标信息
PACSIN 2, a 486 AA phosphoprotein is a novel member of the PACSIN family of cytoplasmic adapter proteins. It is an isoform of PACSIN with a CDC15 N-terminal domain, a C-terminal SH3 domain, 3 conserved regions specific to the PACSIN family, and 3 asn-pro-phe (NPF) motifs, which potentially bind to EH domains. This protein is known to display a ubiquitous expression pattern with the highest levels of expression in brain. Reports suggest that PACSIN 2 participates in the organization of the actin cytoskeleton, the regulation of vesicular traffic. It also participates in endocytic internalization and endocytic receptor recycling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: cytoplasmic phosphoprotein PACSIN2; Protein kinase C and casein kinase substrate in neurons protein 2; RP3-437M21.1; SdpII; syndapin 2; Syndapin II; Syndapin-2; Syndapin-II; syndapin2
基因别名: AI197433; PACSIN2; SDPII
UniProt ID: (Human) Q9UNF0, (Mouse) Q9WVE8
Entrez Gene ID: (Human) 11252, (Mouse) 23970
