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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫组化（冰冻） (IHC (F)) |
1:100 | - |
免疫细胞化学 (ICC/IF) |
1:10-1:500 | - |
流式细胞分析 (Flow) |
1:50-1:100 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human |
宿主/亚型 |
Mouse / IgM |
分类 |
Monoclonal |
类型 |
Antibody |
克隆号 |
DHIC2-5H10 |
抗原 |
Human pancreatic enriched duct cells |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
Conc. Not Determined |
保存液 |
tissue culture supernatant |
内含物 |
0.05% sodium azide |
保存条件 |
4° C, do not freeze |
RRID |
AB_11157232 |
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Programmed cell death protein 2; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8
基因别名: PDCD2; RP8; ZMYND7
UniProt ID: (Human) Q16342
Entrez Gene ID: (Human) 5134
