Invitrogen

PDE3A Polyclonal Antibody

Name: PDE3A Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-82503
Price: 2324.00 CNY
Availability: InStock

高级验证

1 篇参考文献

查看其他21个PDE3A抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (5)
高级验证 (1)

PDE3A Antibody in Immunocytochemistry (ICC/IF)

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PDE3A Antibody (PA5-82503) in ICC/IF

Immunofluorecent analysis of PDE3A in human cell line HeLa using PDE3A Polyclonal Antibody (Product # PA5-82503). Staining shows localization to cytosol.

PDE3A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

PDE3A Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of PDE3A was observed specifically in HeLa cells and in HEK293 cells using anti-PDE3A Polyclonal Antibody (Product #PA5-82503) in western blot. The relative expression levels of PDE3A within each cell line is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image PDE3A Polyclonal Antibody

产品信息

PA5-82503

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

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产品规格

种属反应

Human

已发表种属

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human PDE3A. Recombinant protein control fragment (Product #RP-90769).

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.10 mg/mL

10 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2789661

产品详细信息

Immunogen sequence: SPQILTPPVI CSSCGRPYSQ GNPADEPLER SGVATRTPSR TDDTAQVTSD YETNNNSDSS DIVQNEDETE CLREPLRKAS ACSTYAPETM MFLDKPILAP EPLVMDNLDS IMEQLNT

Highest antigen sequence indentity to the following orthologs: Rat - 82%, Mouse - 81%.

靶标信息

Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: cAMP phosphodiesterase, myocardial cGMP-inhibited; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited cAMP phosphodiesterase; cyclic GMP-inhibited phosphodiesterase A; phosphodiesterase 3A, cGMP-inhibited

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基因别名: CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB

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UniProt ID: (Human) Q14432

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Entrez Gene ID: (Human) 5139

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功能

3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity cGMP-inhibited cyclic-nucleotide phosphodiesterase activity protein binding phosphoric diester hydrolase activity estrogen receptor activity 3',5'-cyclic-GMP phosphodiesterase activity estrogen binding

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