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Invitrogen
PLCD3 Polyclonal Antibody
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产品信息
PA5-84166
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: EGHQSEGLRR FGGAFAPARC LTIAFKGRRK NLDLAAPTAE EAQRWVRGLT KLRARLDAMS QRERLDHWIH SYLHRADSNQ DSKMSFKEIK SLLRMVNVDM NDMYAYLLFK
Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 96%.
靶标信息
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; Phosphoinositide phospholipase C-delta-3; phospholipase C, delta 3; Phospholipase C-delta-3; PLC delta3; PLC-delta-3
基因别名: KIAA1964; PLC-delta-3; PLCD3
UniProt ID: (Human) Q8N3E9
Entrez Gene ID: (Human) 113026
