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This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: OTTHUMP00000031228; P-Rex1; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; PIP3 dependent Rac exchange factor 1; PREX 1; PREX-1; ptdIns(3,4,5)-dependent Rac exchanger 1
基因别名: KIAA1415; P-REX1; PREX1
UniProt ID: (Human) Q8TCU6
Entrez Gene ID: (Human) 57580
分子生物学功能:
guanyl-nucleotide exchange factor