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| 应用 | 建议稀释比 | 已发表文章 |
|---|---|---|
免疫印迹 (WB) |
1:1,000 | - |
| 产品规格 | |
|---|---|
种属反应 |
Human, Mouse, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
A synthesized peptide derived from human PDE3A (Phospho-Ser312) |
偶联物 |
Unconjugated |
形式 |
Liquid |
浓度 |
1 mg/mL |
纯化类型 |
Affinity chromatography |
保存液 |
PBS, pH 7.4, with 50% glycerol |
内含物 |
0.02% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2665303 |
Phospho-PDE3A (Ser312) Polyclonal Antibody detects endogenous levels of PDE3A only when phosphorylated at Ser312.
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least 5 major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cAMP phosphodiesterase, myocardial cGMP-inhibited; CGI-PDE A; cGMP-inhibited 3',5'-cyclic phosphodiesterase A; cGMP-inhibited phosphodiesterase; Cyclic GMP-inhibited phosphodiesterase A; cyclic nucleotide phosphodiesterase; phosphodiesterase 3A, cGMP-inhibited
基因别名: A930022O17Rik; C87899; CGI-PDE; CGI-PDE A; CGI-PDE-A; HTNB; PDE3A; RNPDE3A
UniProt ID: (Human) Q14432, (Mouse) Q9Z0X4, (Rat) Q62865
Entrez Gene ID: (Human) 5139, (Mouse) 54611, (Rat) 50678
分子生物学功能:
phosphodiesterase
