Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
应用 | 建议稀释比 | 已发表文章 |
---|---|---|
免疫印迹 (WB) |
1:1,000 | 查看5篇已发表文章 5篇已发表文章 |
免疫组化 (IHC) |
- | 查看3篇已发表文章 3篇已发表文章 |
免疫细胞化学 (ICC/IF) |
1:250 | 查看2篇已发表文章 2篇已发表文章 |
产品规格 | |
---|---|
种属反应 |
Human, Mouse |
已发表种属 |
Hamster, Human, Mouse, Non-human primate, Rat |
宿主/亚型 |
Rabbit / IgG |
分类 |
Polyclonal |
类型 |
Antibody |
抗原 |
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human Smad3 that contains serine 423 and serine 425. This sequence is conserved in mouse. |
偶联物 |
Unconjugated |
形式 |
Liquid |
纯化类型 |
Antigen affinity chromatography |
保存液 |
Dulbecco's PBS, pH 7.3, with 1mg/mL BSA, 50% glycerol |
内含物 |
0.05% sodium azide |
保存条件 |
-20°C |
RRID |
AB_2533615 |
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; JV15-2; MAD homolog 3; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; MAD-3; mad3; MGC60396; mMad3; Mothers against decapentaplegic homolog 3; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; SMAD 3; SMAD family member 3; SMAD, mothers against DPP homolog 3
基因别名: AU022421; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; SMAD3
UniProt ID: (Human) P84022, (Mouse) Q8BUN5
Entrez Gene ID: (Human) 4088, (Mouse) 17127
分子生物学功能:
DNA-binding transcription factor
gene-specific transcriptional regulator