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Prostaglandin F2- alpha Receptor/PTGFR Antibody (APR-067-200UL) in IHC (F)
Expression of Prostaglandin F2-alpha receptor in mouse hippocampus - Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-Prostaglandin F2- alpha Receptor/PTGFR Antibody (#APR-067) (1:200), followed by goat Anti-rabbit-AlexaFluor-488. PTGFR staining (green) in mouse hippocampal dentate gyrus is detected in cell bodies (arrows). Cell nuclei are stained with DAPI (blue). Mouse... View More
产品信息
APR-067-200UL
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)RSQQHRQGRSHHLE, corresponding to amino acid residues 233-246 of rat Prostaglandin F2- alpha Receptor, 3rd intracellular loop
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F receptor (FP); prostaglandin F2 alpha receptor; Prostaglandin F2-alpha receptor; prostaglandin F2alpha receptor; prostaglandin receptor (2-alpha); Prostanoid FP receptor
基因别名: AI957154; FP; PF2AR; PGF; PTGFR
UniProt ID: (Human) P43088, (Rat) P43118, (Mouse) P43117
Entrez Gene ID: (Human) 5737, (Rat) 25652, (Mouse) 19220
inflammatory response
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
parturition
positive regulation of cell proliferation
positive regulation of gene expression
response to estradiol
response to lipopolysaccharide
calcium-mediated signaling using intracellular calcium source
negative regulation of apoptotic process
cellular response to prostaglandin D stimulus
signal transduction
