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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: GTLDLDKGCT VEELLRGCIE AFDDSGKVRD PQLVRMFLMM HPWYIPSSQL AAKLLHIYQQ SRKDNSNSLQ VKTCHLVRYW ISAFPAEFDL NPELAEQIKE
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Calcium and DAG-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Cdc25-like protein; F25B3.3 kinase-like protein; hCDC25L; RAS guanyl-releasing protein 2
基因别名: CDC25L; MCG7; RASGRP2
Entrez Gene ID: (Human) 10235