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Proteintech
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Sequence of this protein is as follows: MEDSTSPKQE KENQEELGET RRPWEGKTAA SPQYSEPESS EPLEAKQGPE TGRQSRSSRP WSPQSRAKTP LGGPAGPETS SPAPVSPREP SSSPSPLAPA RQDLAAPPQS DRTTSVIPEA GTPYPDPLEQ SSDKRESTPH HTSQSEGNTF QQSQQPKPHL CGRRDVSYNN AKQKELRFDV FQEEDSNSDY DLQQPAPGGS EVAPSMLEIT
This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: radial spoke head 4 homolog A; Radial spoke head protein 4 homolog A; Radial spoke head-like protein 3; radial spokehead-like 3; unnamed protein product
基因别名: A230081C05; CILD11; dJ412I7.1; RSHL3; RSPH4A; RSPH6B
UniProt ID: (Human) Q5TD94, (Mouse) Q8BYM7
Entrez Gene ID: (Human) 345895, (Rat) 309767, (Mouse) 212892