应用 | 建议稀释比 | 已发表文章 |
---|---|---|
对照试剂 (Ctrl) |
Assay-Dependent | - |
产品规格 | |
---|---|
种属 |
Rat |
表达系统 |
E. coli |
氨基酸序列 |
Rat IL-4 recombinant protein contains 121 amino acids |
分子量 |
14 kDa |
分类 |
Recombinant |
类型 |
Protein |
纯度 |
>98% |
偶联物 |
Unconjugated |
形式 |
Lyophilized |
纯化类型 |
Affinity chromatography |
内含物 |
no preservative |
保存条件 |
-20°C |
Description: Interleukin-4 is a potent lymphoid cell growth factor, which stimulates the growth and survivability of certain B and T cells. Recombinant rat IL-4 is a 14 kDa protein containing 121 amino acid residues.
Purity: >98%.
Molecular Weight: 14.0 kDa.
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: B-cell growth factor 1; B-cell IGG differentiation factor; B-cell stimulatory factor 1; BSF-1; H-IL-4; IL-4; ILN; Interleukin; Interleukin-4; Interleukin4; Lymphocyte stimulatory factor 1; M-IL-4; MGC79402
基因别名: Il-4; Il4; Il4e12
UniProt ID: (Rat) P20096
Entrez Gene ID: (Rat) 287287
分子生物学功能:
interleukin superfamily