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Invitrogen
SARS-CoV-2 Omicron Spike Protein S1/S2 (XBB.1) Chimeric Recombinant Human Monoclonal Antibody (D007)
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产品信息
MA5-60608
产品规格
种属反应
Virus
宿主/亚型
Human
/ IgG1, kappa
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
D007
抗原
Recombinant SARS-CoV-2 Omicron XBB.1 Spike ECD Protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Specifically recognize the SARS-CoV-2 Omicron XBB.1 Spike. No cross-reactivity with SARS-CoV-2 XBB.1.5, XBB, BF.7, BA.4/BA.5/BA.5.2, BA.2.75, BQ.1.1, wild type, Alpha, Beta, Delta.. Has cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1) Spike S1+S2 trimer Protein; No cross-reactivity in ELISA with: SARS-CoV-2 Omicron (XBB.1.5) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB.1.5) Spike RBD Protein; SARS-CoV-2 Omicron (XBB) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (XBB) Spike RBD Protein; SARS-CoV-2 Omicron (BF.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4.6/BF.7) Spike RBD Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.4/BA.5/BA.5.2) Spike RBD Protein; SARS-CoV-2 Omicron (B.1.1.529) S1+S2 trimer Protein; SARS-CoV-2 Omicron (B.1.1.529) Spike RBD Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BQ.1.1) Spike RBD Protein; SARS-CoV-2 Omicron (BA.2.75.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Omicron (BA.2.75) Spike RBD Protein; SARS-CoV-2 Delta (B.1.617.2) Spike S1+S2 trimer Protein; SARS-CoV-2 Delta (B.1.617.2) Spike RBD Protein; SARS-CoV-2 Beta (B.1.351) Spike S1+S2 trimer Protein; SARS-CoV-2 Beta (B.1.351, B.1.351.2, B.1.351.3) Spike RBD Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike S1+S2 trimer Protein; SARS-CoV-2 Alpha (B.1.1.7) Spike RBD Protein; SARS-CoV-2 Spike S1+S2 (D614G) trimer Protein; SARS-CoV-2 Spike RBD Protein
靶标信息
The SARS-CoV-2 Omicron Spike Protein S1/S2 refers to specific regions of the spike (S) protein of the Omicron variant of the SARS-CoV-2 virus, which is responsible for COVID-19. The spike protein is a key component of the virus's structure and plays a critical role in its ability to infect host cells. It is composed of two main subunits: S1 and S2. The S1/S2 designation refers to the cleavage site between these two subunits. This cleavage is a crucial step for the activation of the spike protein, which is necessary for the virus to enter host cells. The cleavage is typically performed by host cell proteases, such as furin. The Omicron variant of SARS-CoV-2 has numerous mutations in the spike protein, including in the S1 and S2 subunits. These mutations can affect the virus's transmissibility, ability to evade the immune response, and the effectiveness of vaccines and treatments.
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