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Proteintech
SERPING1/C1 Inactivator Polyclonal Antibody, CoraLite® Plus 488
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
CL488-12259
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
SERPING1/C1 Inactivator fusion protein Ag2819
偶联物
CoraLite® Plus 488
CoraLite® Plus 488
CoraLite® Plus 488
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: LKLYHAFSA MKKVETNMAF SPFSIASLLT QVLLGAGENT KTNLESILSY PKDFTCVHQA LKGFTTKGVT SVSQIFHSPD LAIRDTFVNA SRTLYSSSPR VLSNNSDANL ELINTWVAKN TNNKISRLLD SLPSDTRLVL LNAIYLSAKW KTTFDPKKTR MEPFHFKNSV IKVPMMNSKK YPVAHFIDQT LKAKVGQLQL SHNLSLVILV PQNLKHRLED MEQALSPSVF KAIMEKLEMS KFQPTLLTLP RIKVTTSQDM LSIMEKLEFF DFSYDLNLCG LTEDPDLQVS AMQHQTVLEL TETGVEAAAA SAISVARTLL VFEVQQPFLF MLWDQQHKFP VFMGRVYDPR A
靶标信息
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: anti-thrombin 3; antithrombin; Antithrombin-III; ATIII; C1 esterase inhibitor; C1 Inh; C1 inhibitor; C1-inhibiting factor; complement component 1 inhibitor; Plasma protease C1 inhibitor; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1; serine (or cysteine) proteinase inhibitor, clade G, member 1; Serpin C1; Serpin G1; serpin peptidase inhibitor, clade C, member 1
基因别名: AI114908; At-3; AT3; ATIII; C1IN; C1INH; C1NH; PRO0309; SERPINC1; SERPING1
UniProt ID: (Mouse) P32261, (Mouse) P97290
Entrez Gene ID: (Mouse) 11905, (Mouse) 12258
response to nutrient
blood coagulation
hemostasis
negative regulation of peptidase activity
negative regulation of endopeptidase activity
negative regulation of inflammatory response
regulation of blood coagulation, intrinsic pathway
negative regulation of complement activation, lectin pathway
immune system process
complement activation, classical pathway
regulation of blood coagulation
fibrinolysis
innate immune response
negative regulation of complement activation
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