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Invitrogen
SET Polyclonal Antibody
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图: 1 / 8
SET Antibody (PA5-78163) in ICC/IF
SET Polyclonal Antibody detects SET protein at cytoplasm and nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: SET protein stained by SET Polyclonal Antibody (Product # PA5-78163) diluted at 1:500. Red: alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin Polyclonal Antibody [GT114] (Product # MA5-31466) diluted at 1:1,000. Blue: Hoechst 33342 staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78163
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human SET. The exact sequence is proprietary.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.43 mg/mL
规格
43 µg
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: A431, H1299, HeLa, HepG2, Molt-4, Raji, Neuro 2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12, PC-12, Rat2, C2C12
Predicted Reactivity: Xenopus laevis (99%), Pig (100%), Chicken (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone binding. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: chromatin remodelling factor; HLA-DR-associated protein II; I IGAAD; I-2PP2A; I2PP2A; inhibitor of granzyme A-activated DNase; inhibitor-2 of protein phosphatase-2A; leukemogenesis protein; liver regeneration-related protein LRRG026; liver regeneration-related protein LRRGR00002; OTTHUMP00000022286; phosphatase 2A inhibitor I2PP2A; protein phosphatase type 2A inhibitor; RP11-216B9.3; SET; SET nuclear oncogene; SET nuclear proto-oncogene; SET translocation; SET translocation (myeloid leukemia-associated); TAF-1a; TAF-1b; TAF-I; TAF1; I2PP2A; template-activating factor I; Template-Activating Factor-I, chromatin remodelling factor; unnamed protein product
基因别名: 2610030F17Rik; 2PP2A; 5730420M11Rik; Ab1-115; I-2PP2A; I2PP2A; IGAAD; IPP2A2; MRD58; PHAPII; Set; StF-IT-1; TAF-I; TAF-IBETA
UniProt ID: (Human) Q01105, (Mouse) Q9EQU5, (Rat) Q63945
Entrez Gene ID: (Human) 6418, (Mouse) 56086, (Rat) 307947
nucleosome assembly
negative regulation of neuron apoptotic process
endothelial cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
DNA replication
base-excision repair
nucleosome disassembly
granzyme-mediated apoptotic signaling pathway
regulation of transferase activity
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