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Proteintech
THOP1 Polyclonal Antibody
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产品信息
11738-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
THOP1 Fusion Protein Ag2268 (344-689 aa encoded by BC000135)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VEETRYCVD QNLLKEYFPV QVVTHGLLGI YQELLGLAFH HEEGASAWHE DVRLYTARDA ASGEVVGKFY LDLYPREGKY GHAACFGLQP GCLRQDGSRQ IAIAAMVANF TKPTADAPSL LQHDEVETYF HEFGHVMHQL CSQAEFAMFS GTHVERDFVE APSQMLENWV WEQEPLLRMS RHYRTGSAVP RELLEKLIES RQANTGLFNL RQIVLAKVDQ ALHTQTDADP AEEYARLCQE ILGVPATPGT NMPATFGHLA GGYDAQYYGY LWSEVYSMDM FHTRFKQEGV LNSKVGMDYR SCILRPGGSE DASAMLRRFL GRDPKQDAFL LSKGLQVGGC EPEPQVC (344-689 aa encoded by BC000135 )
靶标信息
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.4.24; EC 3.4.24.15; Endo-oligopeptidase A; Endopeptidase 24.15; metalloendopeptidase; MP78; PZ-peptidase; Soluble metallo-endopeptidase; Thimet oligopeptidase
基因别名: AI131655; AI327041; EP24.15; MEPD_HUMAN; MP78; THOP1; TOP
UniProt ID: (Human) P52888, (Mouse) Q8C1A5, (Rat) P24155
Entrez Gene ID: (Human) 7064, (Mouse) 50492, (Rat) 64517
